Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIV-vaccinia challenge

Mucosal tissues are major sites of HIV entry and initial infection. Thus, the induction of a mucosal cytotoxic T lymphocyte (CTL) response is an important feature for an effective HIV vaccine. However, little is known about approaches to induce such a protective CTL response in the mucosa. Here for...

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Hlavní autoři: Belyakov, Igor M., Derby, Michael A., Ahlers, Jeffrey D., Kelsall, Brian L., Earl, Patricia, Moss, Bernard, Strober, Warren, Berzofsky, Jay A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1998
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC19159/
https://ncbi.nlm.nih.gov/pubmed/9465081
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