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Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation.

A comparison of picornavirus internal ribosome entry site (IRES) secondary structures revealed the existence of conserved motifs located on loops. We have carried out a mutational analysis to test their requirement for IRES-driven translation. The GUAA sequence, located in the aphthovirus 3A loop, d...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: López de Quinto, S, Martínez-Salas, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191578/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094703/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.4171-4175.1997
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