Biodegradable Poly(2-Dimethylamino Ethylamino)Phosphazene for In Vivo Gene Delivery to Tumor Cells. Effect of Polymer Molecular Weight

PURPOSE: Previously, we have shown that complexes of plasmid DNA with the biodegradable polymer poly(2-dimethylamino ethylamino)phosphazene (p(DMAEA)-ppz) mediated tumor selective gene expression after intravenous administration in mice. In this study, we investigated the effect of p(DMAEA)-ppz mole...

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Bibliographic Details
Main Authors: de Wolf, Holger K., de Raad, Markus, Snel, Cor, van Steenbergen, Mies J., Fens, Marcel H. A. M., Storm, Gert, Hennink, Wim E.
Format: Artigo
Language:Inglês
Published: Kluwer Academic Publishers-Plenum Publishers 2007
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915646/
https://ncbi.nlm.nih.gov/pubmed/17435970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-007-9299-z
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