Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard.

The product of the human immunodeficiency virus type 1 (HIV-1) vpr gene induces cell cycle arrest in the G2 phase of the cell cycle and is characterized by an accumulation of the hyperphosphorylated form of cdc2 kinase. This phenotype is similar to the effect of DNA-damaging agents, which can also c...

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Bibliografiska uppgifter

I publikationen:	J Virol
Huvudupphov:	Poon, B, Jowett, J B, Stewart, S A, Armstrong, R W, Rishton, G M, Chen, I S
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 1997
Ämnen:	Research Article
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3961-3971.1997
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