Protein interactions in the herpes simplex virus type 1 VP16-induced complex: VP16 peptide inhibition and mutational analysis of host cell factor requirements.

The herpes simplex virus VP16 protein functions as a potent transcriptional activator and targets DNA sites with the consensus TAATGARAT present in all the viral immediate-early gene promoters. To do so, VP16 directs assembly of a multiprotein complex involving two cellular proteins, host cell facto...

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Main Authors: Simmen, K A, Newell, A, Robinson, M, Mills, J S, Canning, G, Handa, R, Parkes, K, Borkakoti, N, Jupp, R
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC191540/
https://ncbi.nlm.nih.gov/pubmed/9094665
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