Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells.

The hepatitis C virus (HCV) nonstructural 3 protein (NS3) is a 70-kDa multifunctional enzyme with three known catalytic activities segregated in two somewhat independent domains. The essential machinery of a serine protease is localized in the N-terminal one-third of the protein, and nucleoside trip...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Morgenstern, K A, Landro, J A, Hsiao, K, Lin, C, Gu, Y, Su, M S, Thomson, J A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191527/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3767-3775.1997
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