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Oligosaccharides in the stem region maintain the influenza virus hemagglutinin in the metastable form required for fusion activity.

The influenza A virus hemagglutinin (HA) has three conserved oligosaccharides located in the stem region at asparagine residues 12, 28, and 478. The biological role of these oligosaccharides has been investigated by mutational analysis of HA of fowl plague virus that was expressed from a simian viru...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Ohuchi, R, Ohuchi, M, Garten, W, Klenk, H D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191521/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3719-3725.1997
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