A papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retention.

Papillomavirus DNA persists in infected cells as a nuclear plasmid, causing epithelial lesions in many hosts, including humans. The viral protein E2 is required for both replication and transcription to facilitate this persistence. Bovine papillomavirus E2 protein is phosphorylated at two predominan...

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Dettagli Bibliografici
Autori principali: Lehman, C W, King, D S, Botchan, M R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC191514/
https://ncbi.nlm.nih.gov/pubmed/9094639
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