p300 binding by E1A cosegregates with p53 induction but is dispensable for apoptosis.
E1A expression during adenovirus infection induces apoptosis. E1A expression causes accumulation of the p53 tumor suppressor protein, and E1A-induced apoptosis is p53 mediated in primary rodent cells, implying that p53 induction may be linked to apoptosis induction by E1A. Adenoviruses containing mu...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3515-3525.1997 |
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