Immunization with nonstructural proteins promotes functional recovery of alphavirus-infected neurons.

The encephalitic alphaviruses are useful models for understanding virus-neuron interactions. A neurovirulent strain of Sindbis virus (NSV) causes fatal paralysis in mice by infecting motor neurons and inducing apoptosis of these nonrenewable cells. Antibodies to the surface glycoproteins suppress vi...

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Publié dans:	J Virol
Auteurs principaux:	Gorrell, M D, Lemm, J A, Rice, C M, Griffin, D E
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094611/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3415-3419.1997
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