Prenatal detection of chromosome aneuploidies in uncultured chorionic villus samples by FISH.

We developed a 1-d FISH assay for detection of numerical chromosome abnormalities in uncultured chorionic villus samples (CVS). Probes specific for chromosomes 13, 18, 21, X, and Y were used to determine ploidy by analysis of signal number in hybridized nuclei. Aneuploidy detection using this assay...

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Bibliografiska uppgifter
Huvudupphovsmän: Bryndorf, T., Christensen, B., Vad, M., Parner, J., Carelli, M. P., Ward, B. E., Klinger, K. W., Bang, J., Philip, J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914799/
https://ncbi.nlm.nih.gov/pubmed/8808609
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