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Founder effect and prevalence of myotonic dystrophy in South Africans: molecular studies.

A high prevalence of myotonic dystrophy (DM) has been described in South African Caucasoid Afrikaans-speaking families in the northern Transvaal. Evidence is presented for a strong founder effect, with a single haplotype occurring on 68% of all Caucasoid DM chromosomes; among the Afrikaans speakers,...

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Main Authors: Goldman, A., Krause, A., Ramsay, M., Jenkins, T.
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914714/
https://ncbi.nlm.nih.gov/pubmed/8755933
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