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Ascertainment bias in estimates of average heterozygosity.

Population geneticists work with a nonrandom sample of the human genome. Conventional practice ensures that unusually variable loci are most likely to be discovered and thus included in the sample of loci. Consequently, estimates of average heterozygosity are biased upward. In what follows we descri...

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Bibliografske podrobnosti
Main Authors: Rogers, A. R., Jorde, L. B.
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914628/
https://ncbi.nlm.nih.gov/pubmed/8651264
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