Founding BRCA1 mutations in hereditary breast and ovarian cancer in southern Sweden.

Nine different germ-line mutations in the BRCA1 breast and ovarian cancer susceptibility gene were identified in 15 of 47 kindreds from southern Sweden, by use of SSCP and heteroduplex analysis of all exons and flanking intron region and by a protein-truncation test for exon 11, followed by direct s...

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Detalhes bibliográficos
Main Authors: Johannsson, O., Ostermeyer, E. A., Håkansson, S., Friedman, L. S., Johansson, U., Sellberg, G., Brøndum-Nielsen, K., Sele, V., Olsson, H., King, M. C., Borg, A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914564/
https://ncbi.nlm.nih.gov/pubmed/8644702
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