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Adeno-associated virus type 2 DNA replication in vivo: mutation analyses of the D sequence in viral inverted terminal repeats.

The adeno-associated virus type 2 (AAV) genome contains inverted terminal repeats (ITRs) of 145 nucleotides. The terminal 125 nucleotides of each ITR form palindromic hairpin (HP) structures that serve as primers for AAV DNA replication. These HP structures also play an important role in integration...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Wang, X S, Qing, K, Ponnazhagan, S, Srivastava, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191438/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060669/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.3077-3082.1997
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