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Alteration of a single serine in the basic domain of the Epstein-Barr virus ZEBRA protein separates its functions of transcriptional activation and disruption of latency.

The ZEBRA protein from Epstein-Barr virus (EBV) activates a switch from the latent to the lytic expression program of the virus. ZEBRA, a member of the bZIP family of DNA-binding proteins, is a transcriptional activator capable of inducing expression from viral lytic cycle promoters. It had previous...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Francis, A L, Gradoville, L, Miller, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060666/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.3054-3061.1997
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