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Absence of an adipogenic effect of rosiglitazone on mature 3T3-L1 adipocytes: increase of lipid catabolism and reduction of adipokine expression

AIMS/HYPOTHESIS: The thiazolidinedione (TZD) rosiglitazone is a peroxisome proliferator-activated receptor-γ agonist that induces adipocyte differentiation and, hence, lipid accumulation. This is in apparent contrast to the long-term glucose-lowering, insulin-sensitising effect of rosiglitazone. We...

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Main Authors: Wang, P., Renes, J., Bouwman, F., Bunschoten, A., Mariman, E., Keijer, J.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914285/
https://ncbi.nlm.nih.gov/pubmed/17245590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-006-0565-0
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