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Activation of Class I transcription factors by low level Sonic hedgehog signaling is mediated by Gli2-dependent and independent mechanisms

The partitioning of the ventral neural tube into five distinct neuronal progenitor domains is dependent on the morphogenic action of the secreted protein Sonic hedgehog (Shh). The prevailing model stipulates that Class I genes are repressed and Class II genes are activated by high levels of Shh sign...

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Autori principali: Pachikara, Abraham, Dolson, Diane K., Martinu, Lenka, Riccomagno, Martin M., Jeong, Yongsu, Epstein, Douglas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914214/
https://ncbi.nlm.nih.gov/pubmed/17321515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.01.035
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