Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing

Eukaryotic translation initiation factor eIF5B is a ribosome-dependent GTPase that mediates displacement of initiation factors from the 40S ribosomal subunit in 48S initiation complexes and joining of 40S and 60S subunits. Here, we determined eIF5B's position on 80S ribosomes by directed hydrox...

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Bibliographic Details
Main Authors: Unbehaun, Anett, Marintchev, Assen, Lomakin, Ivan B, Didenko, Tatyana, Wagner, Gerhard, Hellen, Christopher U T, Pestova, Tatyana V
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914099/
https://ncbi.nlm.nih.gov/pubmed/17568775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601751
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