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Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components

Pre-mRNA splicing not only removes introns and joins exons to generate spliced mRNA but also results in remodeling of the spliced messenger ribonucleoprotein, influencing various downstream events. This remodeling includes the loading of an exon–exon junction complex (EJC). It is unclear how the spl...

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Detalhes bibliográficos
Main Authors: Zhang, Zuo, Krainer, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913901/
https://ncbi.nlm.nih.gov/pubmed/17606899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704946104
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