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Reduced gap junctional coupling leads to uncorrelated motor neuron firing and precocious neuromuscular synapse elimination

During late embryonic and early postnatal life, neuromuscular junctions undergo synapse elimination that is modulated by patterns of motor neuron activity. Here, we test the hypothesis that reduced spinal neuron gap junctional coupling decreases temporally correlated motor neuron activity that, in t...

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Библиографические подробности
Главные авторы: Personius, Kirkwood E., Chang, Qiang, Mentis, George Z., O'Donovan, Michael J., Balice-Gordon, Rita J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913899/
https://ncbi.nlm.nih.gov/pubmed/17609378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703357104
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