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Structure-Based Functional Analysis of the Replication Protein of Plasmid R6K: Key Amino Acids at the π/DNA Interface

In previous work, we characterized the bases in an iteron of plasmid R6K that are important for the binding of π protein monomers and dimers. Here we investigate the following six amino acids of π, encoded by pir, hypothesized to be important for DNA contact: Ser71, Try74, Gly131, Gly211, Arg225, an...

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Detalhes bibliográficos
Main Authors: Kunnimalaiyaan, Selvi, Rakowski, Sheryl A., Filutowicz, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913429/
https://ncbi.nlm.nih.gov/pubmed/17449630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00109-07
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