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Identification of Critical Residues in the Propeptide of LasA Protease of Pseudomonas aeruginosa Involved in the Formation of a Stable Mature Protease

LasA protease is a 20-kDa elastolytic and staphylolytic enzyme secreted by Pseudomonas aeruginosa. LasA is synthesized as a preproenzyme that undergoes proteolysis to remove a 22-kDa amino-terminal propeptide. Like the propeptides of other bacterial proteases, the LasA propeptide may act as an intra...

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Auteurs principaux: Grande, Kerian K., Gustin, Jean K., Kessler, Efrat, Ohman, Dennis E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913401/
https://ncbi.nlm.nih.gov/pubmed/17351039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01828-06
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