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Thermostabilizing Mutations in Reovirus Outer-Capsid Protein μ1 Selected by Heat Inactivation of Infectious Subvirion Particles
The 76-kDa μ1 protein of nonfusogenic mammalian reovirus is a major component of the virion outer capsid, which contains 200 μ1 trimers arranged in an incomplete T=13 lattice. In virions, μ1 is largely covered by a second major outer-capsid protein, σ3, which limits μ1 conformational mobility. In in...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1913285/ https://ncbi.nlm.nih.gov/pubmed/17208266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.11.024 |
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