Inhibition of Type III Secretion in Salmonella enterica Serovar Typhimurium by Small-Molecule Inhibitors

Type III secretion systems (T3SS) are conserved in many pathogenic gram-negative bacteria. Small molecules that specifically target T3SS in Yersinia and Chlamydia spp. have recently been identified. Here we show that two such compounds inhibit Salmonella T3SS-1, preventing secretion of T3SS-1 effect...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hudson, Debra L., Layton, Abigail N., Field, Terry R., Bowen, Alison J., Wolf-Watz, Hans, Elofsson, Mikael, Stevens, Mark P., Galyov, Edouard E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2007
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913257/
https://ncbi.nlm.nih.gov/pubmed/17502403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01492-06
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