A Killed, Genetically Engineered Derivative of a Wild-Type Extraintestinal Pathogenic E. coli strain is a Vaccine Candidate

Infections due to extraintestinal pathogenic E. coli (ExPEC) result in significant morbidity, mortality and increased healthcare costs. An efficacious vaccine against ExPEC would be desirable. In this report we explore the use of killed-whole E. coli as a vaccine immunogen. Given the diversity of ca...

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Detalhes bibliográficos
Main Authors: Russo, Thomas A., Beanan, Janet M., Olson, Ruth, Genagon, Stacy A., MacDonald, Ulrike, Cope, John J., Davidson, Bruce A., Johnston, Brian, Johnson, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913199/
https://ncbi.nlm.nih.gov/pubmed/17306426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.01.100
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