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Construction of a genome-length cDNA clone for human astrovirus serotype 1 and synthesis of infectious RNA transcripts.

We have constructed a genome-length cDNA clone for human astrovirus serotype 1. When a human colon cancer-derived cell line, CaCo-2, is transfected with RNA transcribed in vitro from this cDNA clone, infectious virus is produced at titers close to those observed after infection with intact astroviru...

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Библиографические подробности
Опубликовано в::J Virol
Главные авторы: Geigenmüller, U, Ginzton, N H, Matsui, S M
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1997
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191237/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995706/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1713-1717.1997
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