Construction of a genome-length cDNA clone for human astrovirus serotype 1 and synthesis of infectious RNA transcripts.

We have constructed a genome-length cDNA clone for human astrovirus serotype 1. When a human colon cancer-derived cell line, CaCo-2, is transfected with RNA transcribed in vitro from this cDNA clone, infectious virus is produced at titers close to those observed after infection with intact astroviru...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Geigenmüller, U, Ginzton, N H, Matsui, S M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1713-1717.1997
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