Mutations in the matrix protein of human immunodeficiency virus type 1 inhibit surface expression and virion incorporation of viral envelope glycoproteins in CD4+ T lymphocytes.

Highly conserved amino acids in the second helix structure of the human immunodeficiency virus type 1 (HIV-1) MA protein were identified to be critical for the incorporation of viral Env proteins into HIV-1 virions from transfected COS-7 cells. The effects of these MA mutations on viral replication...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lee, Y M, Tang, X B, Cimakasky, L M, Hildreth, J E, Yu, X F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1443-1452.1997
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