A novel cellular site-specific DNA-binding protein cooperates with the viral NS1 polypeptide to initiate parvovirus DNA replication.

Replication of linear single-stranded parvovirus DNA proceeds by a rolling-hairpin mechanism which generates long, palindromic, duplex concatamers. Processing to monomer length requires initiation from origins of DNA replication located at the 3' and 5' ends of each embedded monomer, reactions which...

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Vydáno v:	J Virol
Hlavní autoři:	Christensen, J, Cotmore, S F, Tattersall, P
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995666/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1405-1416.1997
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