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Toward highly efficient cell-type-specific gene transfer with retroviral vectors displaying single-chain antibodies.

Recently, we constructed retroviral vector particles derived from spleen necrosis virus (SNV) that display a single-chain antibody (scA) on the viral surface. By transient transfection protocols, we showed that such particles are competent for infection and cell type specific. Efficient infection wa...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Chu, T H, Dornburg, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191105/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985404/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.720-725.1997
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