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Ultrastructural Evidence for Leakage of Lysosomal Contents After Phagocytosis of Monosodium Urate Crystals: A Mechanism of Gouty Inflammation

To obtain direct evidence for the mechanism involved in gouty inflammation, human leukocytes were incubated with synthetic monosodium urate microcrystals. To trace the phago(lyso)somal contents, colloidal carbon, ferritin, Thorotrast® or horseradish peroxidase was added to the incubation medium, or...

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Detalhes bibliográficos
Main Authors: Shirahama, Tsuranobu, Cohen, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1910876/
https://ncbi.nlm.nih.gov/pubmed/4370533
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