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Evidence for CD8+ T-cell immunity to murine rotavirus in the absence of perforin, fas, and gamma interferon.

We recently showed that class I-restricted CD8+ T cells mediate clearance of primary rotavirus infection in mice: JHD knockout (JHD -/-) (B-cell-deficient) mice depleted of CD8+ T cells become chronically infected with murine rotavirus, and beta2 microglobulin knockout (beta2m -/-) mice have delayed...

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Udgivet i:J Virol
Principais autores: Franco, M A, Tin, C, Rott, L S, VanCott, J L, McGhee, J R, Greenberg, H B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.479-486.1997
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