Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2.

DNA vaccines encoding a viral protein have been shown to induce antiviral immune responses and provide protection against subsequent viral challenge. In this study, we show that the efficacy of a DNA vaccine can be greatly improved by simultaneous expression of interleukin-2 (IL-2). Plasmid vectors...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Chow, Y H, Huang, W L, Chi, W K, Chu, Y D, Tao, M H
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191037/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985336/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.169-178.1997
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