Binding kinetics and antiplatelet activities of picotamide, a thromboxane A2 receptor antagonist.

1. Picotamide was shown to inhibit platelet binding of thromboxane A2 (TxA2)-mimetics and to cause a reduction of TxA2 platelet receptors after in vivo administration. The present study aimed to investigate directly [3H]-picotamide binding to human platelets and in particular the relationship betwee...

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Autores principales: Modesti, P. A., Cecioni, I., Colella, A., Costoli, A., Paniccia, R., Neri Serneri, G. G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1910277/
https://ncbi.nlm.nih.gov/pubmed/8032666
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