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Role of CD18 in the accumulation of eosinophils and neutrophils and local oedema formation in inflammatory reactions in guinea-pig skin.

1. Intradermal injection of the complement fragment C5a des Arg induces local oedema formation that, in rabbits and man, is dependent on circulating neutrophils. Monoclonal antibodies to the leukocyte adhesion molecule CD11/CD18 block neutrophil accumulation and prevent neutrophil-dependent oedema f...

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Autores principales: Teixeira, M. M., Reynia, S., Robinson, M., Shock, A., Williams, T. J., Williams, F. M., Rossi, A. G., Hellewell, P. G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1910091/
https://ncbi.nlm.nih.gov/pubmed/7912627
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