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Mechanism underlying substance P-induced relaxation in dog isolated superficial temporal arteries.

1. In helical strips of dog superficial temporal arteries with intact endothelium, substance P elicited a concentration-related relaxation with an EC50 of 2.8 (2.4-3.2) x 10(-10) M. 2. The relaxant response to the peptide in low concentrations (1-4 x 10(-10) M) sufficient to produce approximately ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Enokibori, M., Okamura, T., Toda, N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1910053/
https://ncbi.nlm.nih.gov/pubmed/7516804
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