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Mg(2+)-dependent inhibition of KATP by sulphonylureas in CRI-G1 insulin-secreting cells.

1 Patch-clamp recording techniques were used to examine the effects of tolbutamide, glibenclamide, meglitinide and thiopentone on KATP in CRI-GI insulin-secreting cells in the presence and absence of Mg2+. 2 In the absence of Mg2+ in the intracellular bathing solution, tolbutamide was significantly...

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Bibliografische gegevens
Hoofdauteurs: Lee, K., Ozanne, S. E., Hales, C. N., Ashford, M. L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909971/
https://ncbi.nlm.nih.gov/pubmed/8004407
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