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Potent block of volume-activated chloride currents in endothelial cells by the uncharged form of quinine and quinidine.

1. The effects of quinine and quinidine on the volume-activated chloride current (ICl(vol)) in cultured endothelial cells from bovine pulmonary artery were studied by use of the whole-cell patch-clamp technique. 2. At pH 7.4 both quinine and quinidine induced a fast and reversible block of ICl(vol))...

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Detalhes bibliográficos
Main Authors: Voets, T., Droogmans, G., Nilius, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909854/
https://ncbi.nlm.nih.gov/pubmed/8842456
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