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Necessity of dual blockade of endothelin ETA and ETB receptor subtypes for antagonism of endothelin-1-induced contraction in human bronchi.

1. Endothelin (ET)-1 has been postulated to be involved in the development of obstructive airway diseases in man. In the present study, we attempted to characterize ET receptor subtypes mediating ET-1-induced contraction in human isolated bronchi. The ET receptor antagonists used in the present stud...

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Autori principali: Fukuroda, T., Ozaki, S., Ihara, M., Ishikawa, K., Yano, M., Miyauchi, T., Ishikawa, S., Onizuka, M., Goto, K., Nishikibe, M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909802/
https://ncbi.nlm.nih.gov/pubmed/8882588
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