Intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle by targeting human immunodeficiency virus type 1 integrase.

Integration of viral DNA into a chromosome of the infected host cell is required for efficient replication of a retroviral genome, and this reaction is mediated by the virus-encoded enzyme integrase (IN). As IN plays a pivotal role in establishing infection during the early stages of the retroviral...

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Detalhes bibliográficos
Main Authors: Levy-Mintz, P, Duan, L, Zhang, H, Hu, B, Dornadula, G, Zhu, M, Kulkosky, J, Bizub-Bender, D, Skalka, A M, Pomerantz, R J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC190979/
https://ncbi.nlm.nih.gov/pubmed/8971011
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