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Thromboxane A2-mediated shape change: independent of Gq-phospholipase C--Ca2+ pathway in rabbit platelets.

1. Thromboxane A2 (TXA2) receptor-mediated signal transduction was investigated in washed rabbit platelets to clarify the mechanisms of induction of shape change and aggregation. 2. The TXA2 agonist, U46619 (1 nM to 10 microM) caused shape change and aggregation in a concentration-dependent manner....

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Main Authors: Ohkubo, S., Nakahata, N., Ohizumi, Y.
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909782/
https://ncbi.nlm.nih.gov/pubmed/8882602
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