Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene.

Two Epstein-Barr virus (EBV)-associated malignancies, nasopharyngeal carcinoma and posttransplant lymphoma, rarely have mutations in the p53 tumor suppressor gene, suggesting that a viral protein interferes with p53 function. The EBV oncogene, LMP1, induces expression of the cellular antiapoptotic g...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Fries, K L, Miller, W E, Raab-Traub, N
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190959/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8970991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8653-8659.1996
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