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Block of pancreatic ATP-sensitive K+ channels and insulinotrophic action by the antiarrhythmic agent, cibenzoline.

1. We investigated the effect of cibenzoline (a class Ia antiarrhythmic drug) on basal insulin secretory activity of rat pancreatic islets and ATP-sensitive K+ channels (KATP) in single pancreatic beta cells of the same species, using radioimmunoassay and patch clamp techniques. 2. Micromolar cibenz...

詳細記述

保存先:
書誌詳細
主要な著者: Ishida-Takahashi, A., Horie, M., Tsuura, Y., Ishida, H., Ai, T., Sasayama, S.
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909573/
https://ncbi.nlm.nih.gov/pubmed/8732286
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