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Vaccinia virions lacking the RNA helicase nucleoside triphosphate phosphohydrolase II are defective in early transcription.

Temperature-sensitive mutations (ts10, ts18, and ts39) of the vaccinia virus RNA helicase nucleoside triphosphate phosphohydrolase II (NPH-II) result in the production of noninfectious progeny virions at the restrictive temperature. The noninfectious mutant particles contain the wild-type complement...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Gross, C H, Shuman, S
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190947/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8970979/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8549-8557.1996
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