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Enzymatic synthesis of UTP gamma S, a potent hydrolysis resistant agonist of P2U-purinoceptors.

1. The defective Cl- secretion characteristic of cystic fibrosis airway epithelial cells can be bypassed by an alternative Ca2+ dependent Cl- secretory pathway that is activated by extracellular nucleotides, e.g. uridine-5'triphosphate (UTP), acting on P2U purinoceptors. Since UTP is susceptibl...

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Detalhes bibliográficos
Main Authors: Lazarowski, E. R., Watt, W. C., Stutts, M. J., Brown, H. A., Boucher, R. C., Harden, T. K.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909382/
https://ncbi.nlm.nih.gov/pubmed/8825364
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