A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome.

Persistent infection of C3H/St mice with certain strains of lymphocytic choriomeningitis virus (LCMV) causes a growth hormone (GH) deficiency syndrome (GHDS) manifested as growth retardation and hypoglycemia. Infected mice show high levels of viral replication in the GH-producing cells in the anteri...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Teng, M N, Borrow, P, Oldstone, M B, de la Torre, J C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8970965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.12.8438-8443.1996
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