The pharmacology of GR203040, a novel, potent and selective non-peptide tachykinin NK1 receptor antagonist.

1. The in vitro and in vivo pharmacology of GR203040 ((2S, 3S)-2-methoxy-5-tetrazol-1-yl-benzyl-(2-phenyl-piperidin-3-y l)-amine), a novel, highly potent and selective non-peptide tachykinin NK1 receptor antagonist, was investigated in the present study. 2. GR203040 potently inhibited [3H]-substance...

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Egile Nagusiak: Beattie, D. T., Beresford, I. J., Connor, H. E., Marshall, F. H., Hawcock, A. B., Hagan, R. M., Bowers, J., Birch, P. J., Ward, P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909174/
https://ncbi.nlm.nih.gov/pubmed/8719789
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