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The broad-spectrum anti-emetic activity of the novel non-peptide tachykinin NK1 receptor antagonist GR203040.

1. Following our earlier observations that the tachykinin NK1 receptor antagonist CP-99,994 is an effective anti-emetic in ferrets, we have examined the anti-emetic effects of a more potent and novel NK1 receptor antagonist, GR203040, against various emetic stimuli in the ferret, dog and house musk...

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Main Authors: Gardner, C. J., Twissell, D. J., Dale, T. J., Gale, J. D., Jordan, C. C., Kilpatrick, G. J., Bountra, C., Ward, P.
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909155/
https://ncbi.nlm.nih.gov/pubmed/8719790
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