Activation of phospholipase C in SH-SY5Y neuroblastoma cells by potassium-induced calcium entry.

1. We used SH-SY5Y human neuroblastoma cells to investigate whether depolarization with high K+ could stimulate inositol (1,4,5)trisphosphate (Ins(1,4,5)P3) formation and, if so, the mechanism involved. 2. Ins(1,4,5)P3 was measured by a specific radioreceptor mass assay, whilst [Ca2+]i was measured...

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Bibliografiske detaljer
Main Authors: Smart, D., Wandless, A., Lambert, D. G.
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909103/
https://ncbi.nlm.nih.gov/pubmed/8528562
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